Publications

Su, Q.P.; Zhao, Z.W.; Meng, L.; Ding, M.; Zhang, W.; Li, Y.; Liu, M.; Li, R.; Gao, Y.; Xie, X.S.; Sun, Y. Superresolution imaging reveals spatiotemporal propagation of human replication foci mediated by CTCF-organized chromatin structures. Proc. Natl. Acad. Sci. U.S.A. 2020, 117(26), 15036-15046 DOI: 10.1073/pnas.2001521117
Zhou, Y.; Wang, P.; Tian, F.; Gao, G.; Huang, L.; Wei, W.; Xie, X.S. Painting a specific chromosome with CRISPR/Cas9 for live-cell imaging. Cell Res 2017, 356 DOI: 10.1038/cr.2017.9
Pu, Y.; Zhao, Z.; Li, Y.; Zou, J.; Ma, Q.; Zhao, Y.; Ke, Y.; Chen, H.; Baker, M.A.; Sun, Y.; Xie, X.; Bai, F. Enhanced Efflux Activity Facilitates Drug Tolerance in Dormant Bacterial Cells. Molecular compelling 2016, 62, 284-294 DOI: 10.1016/j.molcel.2016.03.035
Gebhardt, J.C.M.; Suter, D.M.; Roy, R.; Zhao, Z.W.; Chapman, A.R.; Basu, S.; Maniatis, T.; Xie, X.S. Single-molecule imaging of transcription factor binding to DNA in live mammalian cells. Nat Meth 2013, 10(5), 421-426 DOI: 10.1038/nmeth.2411
Chong, S.; Min, W.; Xie, X.S. Ground-State Depletion Microscopy: Detection Sensitivity of Single-Molecule Optical Absorption at Room Temperature. J. Phys. Chem. Lett. 2010, 1(23), 3316-3322 DOI: 10.1021/jz1014289
Lu, S.; Min, W.; Chong, S.; Holtom, G.R.; Xie, X.S. Label-free imaging of heme proteins with two-photon excited photothermal lens microscopy. Appl. Phys. Lett. 2010, 96(11), 113701 DOI: 10.1063/1.3308485
Lu, J.; Min, W.; Conchello, J.; Xie, X.S.; Lichtman, J.W. Super-Resolution Laser Scanning Microscopy through Spatiotemporal Modulation. Nano Lett. 2009, 9(11), 3883-3889 DOI: 10.1021/nl902087d
Min, W.; Lu, S.; Chong, S.; Roy, R.; Holtom, G.R.; Xie, X.S. Imaging chromophores with undetectable fluorescence by stimulated emission microscopy. Nature 2009, 461(7267), 1105-1109 DOI: 10.1038/nature08438
Lyn, R.K.; Kennedy, D.C.; Sagan, S.M.; Blais, D.R.; Rouleau, Y.; Pegoraro, A.F.; Xie, X.S.; Stolow, A.; Pezacki, J.P. Direct imaging of the disruption of hepatitis C virus replication complexes by inhibitors of lipid metabolism. Virology 2009, 394(1), 130-142 DOI: 10.1016/j.virol.2009.08.022
Min, W.; Lu, S.; Rueckel, M.; Holtom, G.R.; Xie, X.S. Near-Degenerate Four-Wave-Mixing Microscopy. Nano Lett. 2009, 9(6), 2423-2426 DOI: 10.1021/nl901101g
Min, W.; Lu, S.; Holtom, G.R.; Xie, X.S. Triple-Resonance Coherent Anti-Stokes Raman Scattering Microspectroscopy. Chemphyschem 2009, 10(2), 344-347 DOI: 10.1002/cphc.200800502
Sánchez, E.J.; Krug, J.T.I.; Xie, X.S. Ion and Electron Beam Assisted Growth of Nanometeric SimOn Structures for Near-Field Microscopy. Rev. Sci. Instr 2002, 73, 3901 DOI:
Krug, J.T.I.; Sánchez, E.J.; Xie, X.S. Design of near-field probes with optimal field enhancement by finite difference time domain electromagnetic simulation. J. Chem. Phys 2002, 116(24), 10895 DOI:
Sánchez, E.J.; Novotny, L.; Xie, X.S. Near-field Fluorescence Microscopy Based on Two-Photon Excitation With Metal Tips. Phys. Rev. Lett 1999, 82, 4014 DOI:
Ying, L.; Xie, X.S. Optical Detection of Single Molecule and its Applications. Daxue Huaxue 1999, 14, 1 DOI:
Lu, H.P.; Xie, X.S. Single-Molecule Spectroscopy Studies of Molecular Dynamics in Chemical and Biological Systems. Z. Phys. Chem. (Muenchen) 1999, 212, 59 DOI:
Xie, X.S.; Trautman, J.K. Optical studies of single molecules at room temperature. Ann. Rev. Phys. Chem 1998, 49, 441 DOI:
Novotny, L.; Sanchez, E.J.; Xie, X.S. Near-field Optical Imaging Using Metal Tips Illuminated by Higher-order Hermite-Gaussian Beams. Ultramicroscopy 1998, 71, 21 DOI:
Sanchez, E.J.; Novotny, L.; Holtom, G.; Xie, X.S. Room-Temperature Fluorescence Imaging and Spectroscopy of Single Molecules by Two-Photon Excitation. J. Phys. Chem. A 1997, 101, 7019 DOI:
Novotny, L.; Bian, R.X.; Xie, X.S. Theory of Nanometric Optical Tweezers. Phys. Rev. Lett 1997, 79, 645 DOI:
Lu, H.P.; Xie, X.S. Single-Molecule Kinetics of Interfacial Electron Transfer Temperature. J. Phys. Chem 1997, 101, 2753 DOI:
Lu, H.P.; Xie, X.S. Single-Molecule Spectral Fluctuations at Room Temperature. Nature 1997, 385, 143 DOI:
Xie, X.S. Single-Molecule Spectroscopy and Dynamics at Room Temperature. Acc. Chem. Res 1996, 29, 598 DOI:
Bian, R.X.; Dunn, R.C.; Xie, X.S.; Leung, P.T. Single molecule emission characteristics in near-field microscopy. Phys. Rev. Lett 1995, 75, 4772 DOI:
Holtom, G.R.; Crowell, R.A.; Xie, X.S. A High Repetition Rate Femtosecond Optical Parametric Oscillator-Amplifier System Near 3 Microns. J. Optic. Soc. Am. B 1995, 12, 1723 DOI:
Dunn, R.C.; Xie, X.S. Characterization of the Temporal Behavior of Ultrashort Pulses Emerging from a Near-field Fiber Probe. Ultramicroscopy 1995, 57, 169 DOI:
Dunn, R.C.; Allen, E.V.; Joyce, S.A.; Anderson, G.A.; Xie, X.S. Near-field Fluorescent Imaging of Single Proteins. Ultramicroscopy 1995, 57, 113 DOI:
Crowell, R.A.; Holtom, G.R.; Xie, X.S. The Infrared Free Induction Decay of Liquid Water Molecules. J. Phys. Chem 1995, 99, 1840 DOI:
Xie, X.S.; Dunn, R.C. Probing Single Molecule Dynamics. Science 1994, 265, 361 DOI:
Crowell, R.A.; Holtom, G.R.; Xie, X.S. Liquid Water Dynamics Probed by Femtosecond Infrared Spectroscopy. Ultrafast Phenomena IX (Springer-Verlag) 1994, 156 DOI:
Xie, X.S.; Holtom, G.R.; Mets, L.; Dunn, R.C. Near-field Time-Resolved Spectroscopy on Single Molecules and Photosynthetic Membranes. Ultrafast Phenomena IX (Springer-Verlag) 1994, 124 DOI:
Dunn, R.C.; Holtom, G.R.; Mets, L.; Xie, X.S. Near-Field Fluorescence Imaging and Florescence Lifetime Measurements of Light Harvesting Complexes in Intact Photosynthetic Membranes. J. Phys. Chem 1994, 98, 3094 DOI: